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MICa 8012

Integrated Topics in Microbiology, Immunology
and Cancer Biology

Fall Semester 2017
Monday 1:25-3:20

Moos Health Sci Tower 2-120 

 

Instructors:
Ameeta Kelekar         5-3204            ameeta@umn.edu            5-126 MCB
Chris Pennell             5-7138            penne001@umn.edu       460D MCRB

 

Description:
This course is designed for second year students in the MICaB Graduate Program and MSTP students beginning their thesis research in a MICaB mentor’s laboratory. It will help students prepare for the written and oral preliminary examinations by going through how to organize, write, and review grant proposals. It will also provide the scientific basis for an F30/F31 or similar predoctoral fellowship; the student’s thesis advisor needs to help craft the training/career development portion of the predoctoral fellowship.

Textbook:
“A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant” by Andrew D. Hollenbach; ISBN: 978-­0-­12-­420187-­3. Download it for free from the UMN Biomedical library (http://www.sciencedirect.com.ezp2.lib.umn.edu/science/book/9780124201873).

Assignments:
Assignments are to be attached to emails as Word doc or docx files, NOT as pdf files. It’s easier for us to annotate Word files than pdf files. The files should be named as follows: “Your last name, name of assignment” (e.g. Specific Aims paragraphs).

Class List

Name

Email

Degree Sought

Track

Advisor

#

Arvindam, Upasana

arvi0051@umn.edu

PhD

Immunology

Miller

7

Jarvis, Matt

jarvi168@umn.edu

PhD

Cancer Biology

Harris

4

Lee, Robin

leex5749@umn.edu

MD/PhD

Immunology

Farrar

3

McBride, Terri

mcbride@umn.edu

MD/PhD

Cancer Biology

Dehm

2

Nikrad, Julia

nikr0006@umn.edu

PhD

Cancer Biology

Largaespada

10

Pomeroy, Emily

epomeroy@umn.edu

PhD

Cancer Biology

Moriarity

9

Rhee, Stephanie

rheex016@umn.edu

MD/PhD

Immunology

Blazar

5

Robinson, Serina

robi0916@umn.edu

PhD

Microbiology Wackett

8

Rogers, Anna

roger915@umn.edu

PhD

Cancer Biology

Skubitz

1

Sjaastad, Frankie

sjaas004@umn.edu

PhD

Cancer Biology

Griffith

6


# The number in the right-most column was assigned randomly. It is used to determine the due dates of assignments and presentations

Grading: A-F scale 

Participation    5%
Timely submissions 5%
Reviews of other proposals   40% (2x20% each)
Proposal  50%

 

September 11
- Introduction
-Goal is to have a submission-ready grant application by the end of the semester.
-Begin thinking about topic(s) around which you could craft an application.

September 18
-5 x 20 minute discussions of first two specific aims paragraphs by students 1-5.
-No chalk talk required but be prepared to use the board, if need be, to answer questions

September 25
-5 x 20 minute discussions of first two specific aims paragraphs by students 6-10.
-No chalk talk required but be prepared to use the board, if need be, to answer questions

October 2
-5 x 20 minute chalk talks of specific aims by students 1-5.

October 9
-5 x 20 minute chalk talks of specific aims by students 6-10.

October 16
-3 x 30 minute chalk talks of experimental design by students 1-3.

October 23
-3 x 30 minute chalk talks of experimental design by students 4-6.

October 30
-3 x 30 minute chalk talks of experimental design by students 7-9.

November 6
-1 x 30 minute chalk talks of experimental design by student 10.
- 2 x 25-30 minute class discussions of grants from students 1-2.

November 13
-4 x 25-30 minute class discussions of grants from students 3-6.

November 20
-4 x 25-30 minute class discussions of grants from students 7-10.
-Discussion of how the mock study section will proceed.

November 27
-No class.

December 4
-5 x 20min reviews of students 1-5 in a mock study section (2 students + 1 instructor review each grant).

December 11
-45 x 20 min reviews of students6-10 in a mock study section (2 students + 1 instructor review each grant).

Detailed Timeline

 Please note that assignments are to be emailed by noon on the due date, unless otherwise noted (e.g. grant reviews are due by 9:00 am on Dec 5 and Dec 12).

Bold-faced dates indicate Monday classes -

September 11 (Mon)
Introduction: How to craft a grant

    1. Stepwise process
    2. Literature review to identify holes in the field that need to be addressed
    3. Components of the grant
    4. Specific aims – the page that sells the grant
    5. Students – present brief description of proposal topic


September 18 (Mon)

-5 x 20 minute discussions of first two paragraphs of specific aims by students 1-5. Students do not need to use the white board but they certainly may use it if it helps to answer questions.


September 25 (Mon)

-5 x 20 minute discussions of first two paragraphs of specific aims by students 6-10. Students do not need to use the white board but they certainly may use it if it helps to answer questions.

September 29 (Fri – noon)
-Students 1-5 email their complete specific aims page to the class and instructors. Everyone read the documents to prepare for class discussion.

October 2 (Mon)

-5 x 20 minute chalk talks of specific aims by students 1-5.

October 6 (Fri – noon)
-Students 6-10 email their complete specific aims page to the class and instructors. Everyone read the documents to prepare for class discussion.

October 9 (Mon)

-5 x 20 minute chalk talks of specific aims by students 6-10.

October 13 (Fri – noon)
-Students 1-3 email their 1st draft of grant to the class and instructors. Everyone reads them to prepare for class discussion.

October 16 (Mon)

-3 x 30 minute chalk talks of grant by students 1-3. Focus on the proposed experiments.

October 20 (Fri – noon)
-Students 4-6 email their 1st draft of grant to the class and instructors. Everyone reads them to prepare for class discussion.

October 23 (Mon)

-3 x 30 minute chalk talks of experimental design by students 4-6. Focus on the proposed experiments.

October 27 (Fri – noon)
-Students 7-9 email their 1st draft of grant to the class and instructors. Everyone reads them to prepare for class discussion.

October 30 (Mon)

-3 x 30 minute chalk talks of experimental design by students 7-9. Focus on the proposed experiments.

November 3 (Fri – noon)
-Students 10 emaisl 1st draft of grant to the class and instructors. Everyone reads it to prepare for class discussion.
- Students 1-2 email their 2nd draft of grant to the class and instructors. Everyone reads the documents to prepare for class discussion.

November 6 (Mon)

- 3 x 30 minute chalk talks of experimental design by students 10, 1 and 2. Focus on the proposed experiments.

November 10 (Fri - noon)
-Students 3-6 email their 2nd draft of grant to the class and instructors. Everyone reads the documents to prepare for class discussion.

November 13 (Mon)

-4 x 25-30 minute class discussions of grants from students 3-6.

November 15 (Wed – noon)
-Students 1-5 email their final grants to the instructors. Instructors will send the grants to the assigned reviewers.

November 17 (Fri – noon)
-Students 7-10 email their 2nd draft of grant to the class and instructors. Everyone reads the documents to prepare for class discussion.

November 20

-4 x 25-30 minute class discussions of grants from students 7-10.

November 22 (Wed – noon)
-Students 6-10 email their final grants to the instructors. Instructors will send the grants to the assigned reviewers.

November 27 (Mon)

-No class.

December 4 (Mon)

-Students 1-5 email reviews of grants by 9:00 am to instructors.
-5 x 20 min reviews of students 1-5 in a mock study section (2 students + 1 instructor review each grant).

December 11 (Mon) Pennell gone

- Students 6-10 email reviews of grants by 9:00 am to instructors.
-5 x 20 min reviews of students 6-10 in a mock study section (2 students + 1 instructor review each grant).