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MICa 8012

Integrated Topics in Microbiology, Immunology
and Cancer Biology

Fall Semester 2016
Monday 1:25-3:20

Moos Health Sci Tower 2-120 

 

Instructors:
Ameeta Kelekar         5-3204            ameeta@umn.edu            5-126 MCB
Chris Pennell             5-7138            penne001@umn.edu       3-135 CCRB

 

Description:
This course is designed for second year students in the MICaB Graduate Program and MSTP students beginning their thesis research in a MICaB mentor’s laboratory. It will help students prepare for the written and oral preliminary examinations by going through how to organize, write, and review grant proposals. It will also provide the scientific basis for an F30/F31 or similar predoctoral fellowship; the student’s thesis advisor needs to help craft the training/career development portion of the predoctoral fellowship.

Textbook:
“A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant” by Andrew D. Hollenbach; ISBN: 978-­0-­12-­420187-­3. Download it for free from the UMN Biomedical library (http://www.sciencedirect.com.ezp2.lib.umn.edu/science/book/9780124201873).

Assignments:
Assignments are to be attached to emails as Word doc or docx files, NOT as pdf files. It’s easier for us to annotate Word files than pdf files. The files should be named as follows: “Your last name, name of assignment” (e.g. Specific Aims paragraphs).

Class List

Name

Email

Degree Sought

Track

Advisor

#

Chiu, Emily

chiux141@umn.edu

MD/PhD

Immunology

Miller

6

Conley, Bridget

conle215@umn.edu

PhD

Microbiology

Gralnick

7

Fazzino, Lisa

fazzi004@umn.edu

PhD

Microbiology

Harcombe

3

Irey, Emily

ireyx004@umn.edu

PhD

Cancer Biology

Schwertfeger

4

Salgado Barrero, Oscar

salga036@umn.edu

PhD

Immunology

Hogquist

2

Santos Perez, Carlos

santo208@umn.edu

MD/PhD

Cancer Biology

Lange

1

Tucker, Christopher

tucke374@umn.edu

MD/PhD

Immunology

Fife

5

Wijeyesinghe, Sathi

wijey001@umn.edu

MD/PhD

Immunology

Masopust

8


# The number in the right-most column was assigned randomly. It is used to determine the due dates of assignments and presentations

Grading: A-F scale 

Participation    10%
Timely submissions 10%
Reviews of other proposals   30% (2x15% each)
Proposal  50%

 

September 12
- Introduction
-Goal is to have a submission-ready grant application by the end of the semester.
-Begin thinking about topic(s) around which you could craft an application.

September 19
-4 x 25-30 minute discussions of first two specific aims paragraphs by students 1-4.
-No chalk talk required but be prepared to use the board, if need be, to answer questions

September 26
-4 x 25-30 minute discussions of first two specific aims paragraphs by students 5-8.
-No chalk talk required but be prepared to use the board, if need be, to answer questions

October 3
-4 x 25-30 minute chalk talks of specific aims by students 1-4.

October 10
-4 x 25-30 minute chalk talks of specific aims by students 5-8.

October 17
-2 x ≈45 minute chalk talks of experimental design by students 1-2.

October 24
-2 x ≈45 minute chalk talks of experimental design by students 3-4.

October 31
-2 x ≈45 minute chalk talks of experimental design by students 5-6.

November 7
-2 x ≈45 minute chalk talks of experimental design by students 7-8.

November 14
-4 x 25-30 minute class discussions of grants from students 1-4.

November 21
-4 x 25-30 minute class discussions of grants from students 5-8.
-Discussion of how the mock study section will proceed.

November 28
-No class.

December 5
-4 x 25 min reviews of students 1-4 in a mock study section (2 students + 1 instructor review each grant).

December 12
-4 x 25 min reviews of students 5-8 in a mock study section (2 students + 1 instructor review each grant).

Detailed Timeline

 Please note that assignments are to be emailed by noon on the due date, unless otherwise noted (e.g. grant reviews are due by 9:00 am on Dec 5 and Dec 12).

Bold-faced dates indicate Monday classes -

September 12 (Mon)
Introduction: How to craft a grant

    1. Stepwise process
    2. Literature review to identify holes in the field that need to be addressed
    3. Components of the grant
    4. Specific aims – the page that sells the grant
    5. Students – present brief description of proposal topic


September 19 (Mon)

-4 x 25-30 minute discussions of first two paragraphs of specific aims by students 1-4. Students do not need to use the white board but they certainly may use it if it helps to answer questions.


September 26 (Mon)

-4 x 25-30 minute discussions of first two paragraphs of specific aims by students 5-8. Students do not need to use the white board but they certainly may use it if it helps to answer questions.

September 30 (Fri – noon)
-Students 1-4 email their complete specific aims page to the class and instructors. Everyone read the documents to prepare for class discussion.

October 3 (Mon)

-4 x 25-30 minute chalk talks of specific aims by students 1-4.

October 7 (Fri – noon)
-Students 5-8 email their complete specific aims page to the class and instructors. Everyone read the documents to prepare for class discussion.

October 10 (Mon)

-4 x 25-30 minute chalk talks of specific aims by students 5-8.

October 14 (Fri – noon)
-Students 1-2 email their 1st draft of grant to the class and instructors. Everyone read them to prepare for class discussion.

October 17 (Mon)

-2 x ≈45 minute chalk talks of grant by students 1-2.

October 21 (Fri – noon)
-Students 3-4 email their 1st draft of grant to the class and instructors. Everyone read them to prepare for class discussion.

October 24 (Mon)

-2 x ≈45 minute chalk talks of experimental design by students 3-4.

October 28 (Fri – noon)
-Students 5-6 email their 1st draft of grant to the class and instructors. Everyone read them to prepare for class discussion.

October 31 (Mon)

-2 x ≈45 minute chalk talks of experimental design by students 5-6.

November 4 (Fri – noon)
-Students 7-8 email their 1st draft of grant to the class and instructors. Everyone read them to prepare for class discussion.

November 7 (Mon)

-2 x ≈45 minute chalk talks of experimental design by students 7-8.


November 11 (Fri - noon)
-Students 1-4 email their 2nd draft of grant to the class and instructors. Everyone read the documents to prepare for class discussion.

November 14 (Mon)

-4 x 25-30 minute class discussions of grants from students 1-4.

November 16 (Wed – noon)
-Students 1-4 email their final grants to the instructors. Instructors will send the grants to the assigned reviewers.

November 18 (Fri – noon)
-Students 5-8 email their 2nd draft of grant to the class and instructors. Everyone read the documents to prepare for class discussion.

November 21

-4 x 25-30 minute class discussions of grants from students 5-8.

November 23 (Wed – noon)
-Students 5-8 email their final grants to the instructors. Instructors will send the grants to the assigned reviewers.

November 28 (Mon)

-No class.

December 5 (Mon)

-Students 1-4 email reviews of grants by 9:00 am to instructors.
-4 x 25 min reviews of students 1-4 in a mock study section (2 students + 1 instructor review each grant).

December 12 (Mon)

- Students 5-8 email reviews of grants by 9:00 am to instructors.
-4 x 25 min reviews of students 5-8 in a mock study section (2 students + 1 instructor review each grant).