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MICa 8012

Integrated Topics in Microbiology, Immunology
and Cancer Biology

Fall Semester 2018
Wednesday 1:25-3:20

Rm: MoosT-1-430
  

Instructors:
Ameeta Kelekar         5-3204            ameeta@umn.edu            5-126 MCB
Chris Pennell             5-7138            penne001@umn.edu       460D MCRB

 

Description:
This course is designed for second year students in the MICaB Graduate Program and MSTP students beginning their thesis research in a MICaB mentor’s laboratory. It will help students prepare for the written and oral preliminary examinations by going through how to organize, write, and review grant proposals. It will also provide the scientific basis for an F30/F31 or similar predoctoral fellowship; the student’s thesis advisor needs to help craft the training/career development portion of the predoctoral fellowship.

Textbook:

“A Practical Guide to Writing a Ruth L. Kirschstein NRSA Grant” by Andrew D. Hollenbach; ISBN: 978-0-12-420187-3. Download it for free from the UMN Biomedical library

(http://www.sciencedirect.com.ezp2.lib.umn.edu/science/book/9780124201873).

Assignments:

Assignments are to be attached to emails as Word files, NOT as pdf files. It’s easier for us to annotate Word files than pdf files. The files should be named as follows: “Your last name, name of assignment” (e.g. Pennell, Specific Aims paragraphs).

Class List

Name

Email

Degree(s) Sought

Track

Advisor

#

Bolivar Wagers, Sara

boliv004@umn.edu

MD/PhD

Cancer

Blazar

3

Dwyer, Alexander

dwyer171@umn.edu

MD/PhD

Immunology

Fife

9

Gavil, Noah

gavil014@umn.edu

MD/PhD

Immunology

Masopust

6

Jackson, Katrina

jack1324@umn.edu

PhD

Microbiology

Nielsen

14

Lee, Ruth

leex9181@umn.edu

PhD

Microbiology

Gralnick

8

Naumann, Jordan

jnaumann@umn.edu

PhD

Cancer

Harris

12

Osum, Kevin

kcosum@umn.edu

PhD

Immunology

Jenkins

2

Rield (Brekke), Julia

jriedl@umn.edu

MD/PhD

Cancer

Tolar

7

Scott, Milcah

scot0340@umn.edu

PhD

Immunology

Masopust

5

Sjaastad, Lucy

sjaas005@umn.edu

PhD

Immunology

Farrar

13

Smith, Megan

smit7496@umn.edu

PhD

Microbiology

Wackett

1

Titcombe, Philip

titco008@umn.edu

MD/PhD

Immunology

Mueller

10

Villarreal, Alex

villa467@umn.edu

PhD

Microbiology

Hunter

11

Wanhainen, Kelsey

wanha006@umn.edu

MD/PhD

Immunology

Jameson

4


# The number in the right-most column was assigned randomly. It is used to determine the due dates of assignments and presentations

 

 

Grading: A-F scale 

Participation    5%
Timely submissions 5%
Reviews of other proposals   40% (2x20% each)
Proposal  50%

 

September 5
- Introduction
-Goal is to have a submission-ready grant application by the end of the semester.
-Begin thinking about topic(s) around which you could craft an application.

September 12 
-5 x 20 minute discussions of first two specific aims paragraphs by students 1-5.
-No chalk talk required but be prepared to use the board, if need be, to answer questions

September 19 
-5 x 20 minute discussions of first two specific aims paragraphs by students 6-10.
-No chalk talk required but be prepared to use the board, if need be, to answer questions

September 26 
-4 x 20 minute discussions of first two specific aims paragraphs by students 11-14.
-No chalk talk required but be prepared to use the board, if need be, to answer questions

October 3 
-5 x 20 minute chalk talks of specific aims by students 1-5.

October 10 
-5 x 20 minute chalk talks of specific aims by students 6-10.

October 17
-4 x 20 minute chalk talks of specific aims by students 11-14.

October 24
-5 x 20 minute chalk talks of experimental design by students 1-5.

October 31
-5 x 20 minute chalk talks of experimental design by students 6-10.

November 7 
-4 x 20 minute chalk talks of experimental design by students 11-14.

November 14 
-Discussion of how the mock study section will proceed.

November 21 
-No class.

November 28 
-5 x 20 min reviews of students 1-5 in a mock study section (2 students + 1 instructor review each grant).

December 5 
-5 x 20 min reviews of students 6-10 in a mock study section (2 students + 1 instructor review each grant).

December 12 
-4 x 20 min reviews of students 11-14 in a mock study section (2 students + 1 instructor review each grant).

 

Detailed Timeline
Please note that assignments are to be emailed as Word (doc/docx) attachments by noon on the due date, unless otherwise noted (e.g. grant reviews are due by 9:00 am on Nov 28, Dec 5, and Dec 12).
- Bold-faced dates indicate Wednesday classes -
September 5 (Wed)
Introduction: How to craft a grant

  1. Stepwise process
  2. Literature review to identify holes in the field that need to be addressed
  3. Components of the grant
  4. Specific aims – the page that sells the grant 
  5. Students – present brief description of proposal topic

September 12 (Wed)
-5 x 20 minute discussions of first two paragraphs of specific aims by students 1-5. Students do not need to use the white board but they certainly may use it if it helps to answer questions.
September 19 (Wed)
-5 x 20 minute discussions of first two paragraphs of specific aims by students 6-10. Students do not need to use the white board but they certainly may use it if it helps to answer questions.
September 26 (Wed)
-4 x 20 minute discussions of first two paragraphs of specific aims by students 11-14. Students do not need to use the white board but they certainly may use it if it helps to answer questions.
October 1 (Mon – noon)
-Students 1-5 email their complete specific aims page to the class and instructors. Everyone reads the documents to prepare for class discussion.
October 3 (Wed)
-5 x 20 minute chalk talks of specific aims by students 1-5.
October 8 (Mon – noon)
-Students 6-10 email their complete specific aims page to the class and instructors. Everyone reads the documents to prepare for class discussion.
October 10 (Wed)
-5 x 20 minute chalk talks of specific aims by students 6-10.

October 15 (Mon – noon)
-Students 11-14 email their complete specific aims page to the class and instructors. Everyone reads the documents to prepare for class discussion.

October 17 (Wed)
-4 x 20 minute chalk talks of specific aims by students 11-14.

October 22 (Mon – noon)
-Students 1-5 email their grant draft to the class and instructors. Everyone reads them to prepare for class discussion.

October 24 (Wed)
-5 x 20 minute chalk talks of experimental design by students 1-5.

October 29 (Mon – noon)
-Students 6-10 email their grant draft to the class and instructors. Everyone reads them to prepare for class discussion.

October 31 (Wed)
-5 x 20 minute chalk talks of experimental design by students 6-10.

November 5 (Mon – noon)
-Students 11-14 email their grant draft to the class and instructors. Everyone reads them to prepare for class discussion.

November 7 (Wed)
-5 x 20 minute chalk talks of experimental design by students 11-14.

November 14 (Wed)
-Discussion of mock study section

November 19 (Mon - noon)
-Students 1-5 email their final grants to instructors for distribution to reviewers.
November 21 (Wed)
-No class.

November 26 (Mon - noon)
-Students 6-10 email their final grants to instructors for distribution to reviewers.

November 28 (Wed)
-Grant reviews from students 1-5 emailed to instructors by 9 am.
-Mock study section review of grants from students 1-5 (2 students + 1 instructor review each grant).

December 3 (Mon - noon)
-Students 11-14 email their final grants to instructors for distribution to reviewers.

December 5 (Wed)
-Grant reviews from students 6-10 emailed to instructors by 9 am.
-Mock study section review of grants from students 6-10 (2 students + 1 instructor review each grant).

December 12 (Wed)
-Grant reviews from students 11-14 emailed to instructors by 9 am.
-Mock study section review of grants from students 11-14. (2 students + 1 instructor review each grant).

 

Summary of Due Dates


#

Specific Aims

Grant Draft

Grant Final

Reviews

1

Oct 1

Oct 22

Nov 19

Nov 28

2

Oct 1

Oct 22

Nov 19

Nov 28

3

Oct 1

Oct 22

Nov 19

Nov 28

4

Oct 1

Oct 22

Nov 19

Nov 28

5

Oct 1

Oct 22

Nov 19

Nov 28

6

Oct 8

Oct 29

Nov 26

Dec 5

7

Oct 8

Oct 29

Nov 26

Dec 5

8

Oct 8

Oct 29

Nov 26

Dec 5

9

Oct 8

Oct 29

Nov 26

Dec 5

10

Oct 8

Oct 29

Nov 26

Dec 5

11

Oct 15

Nov 5

Dec 3

Dec 12

12

Oct 15

Nov 5

Dec 3

Dec 12

13

Oct 15

Nov 5

Dec 3

Dec 12

14

Oct 15

Nov 5

Dec 3

Dec 12