University of Minnesota
MICaB Graduate Program
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Current Students

Jessica Kotov

Thesis Advisor: Marc Jenkins

Year entered: 2013

Degrees received:
B.S., University of California, San Diego, CA, 2011

Honors and Awards:

  • Dennis W. Watson Fellowship, 2016-2017
  • National Institutes of Health F31 Ruth L. Kirschstein Predoctoral Individual National Research Service Award (F31 AI133716) for 08/17-06/19
  • MICaB Travel Award, Spring Semester 2017
  • Immunology training grant, 2015-2017
  • The Elkes Foundation Scholarship to attend Keystone Symposia: B cells at the Intersection of Innate and Adaptive Immunity (E3), Stockholm, Sweden, 2016

My project involves studying CD4 T cell help to B cells. This involves better understanding what B cell help functions each CD4 T cell subset provides. More specifically, I seek to determine how each subset influences germinal center/memory B cell formation and isotype switching. While many of these questions have been answered, previous work heavily relied on in vitro data or the use of transgenic systems. We are reanswering these basic CD4 T cell biology questions in vivo using an antigen-specific endogenously derived polyclonal system.


  • Yang, J.A., N.J. Tubo, M.D. Gearhart, V.J. Bardwell and M.K. Jenkins. 2015. Cutting Edge: Bcl6-Interacting Corepressor Contributes to Germinal Center T Follicular Helper Cell Formation and B Cell Helper Function. J Immunol. 194:5604-5608.
  • Schmiel SE, Yang JA, Jenkins MK, Mueller DL. Cutting Edge: Adenosine A2a receptor signals inhibit germinal center T follicular helper cell differentiation during the primary response to vaccination. J Immunol. 2017;198(2)623-628.