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Jeffrey A. Gralnick , Ph.D.
Assistant Professor
Department of Microbiology and BioTechnology Institute
University of Wisconsin, Madison, 2003 , Ph.D.
gralnick@umn.edu
612-626-6496 - office
612-624-3891 - lab
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Research Interests:
Physiology of Shewanella; Geomicrobiology
I am interested in understanding the physiology of Shewanella, a species of gram-negative bacteria found throughout the world in aquatic environments. This group has the greatest diversity of compounds it can ‘breathe’ of any organisms studied to date. The act of respiring these compounds can impact geochemical gradients of compounds like sulfur, iron and manganese. For instance, S. oneidensis can respire insoluble manganese and iron oxide minerals, promoting their dissolution. The molecular mechanism that enables S. oneidensis to carry out these reactions and how these systems are regulated will be a main focus of research in my laboratory. By understanding the mechanistic details of these processes, not only can we begin to rationally engineer organisms like S. oneidensis for biotechnological applications, ranging from bioremediation to energy generation, but we will also begin to understand how Shewanella thrives in the environment.
Lab website
http://www.bti.umn.edu/gralnick/
Recent publications
- Lies, D.P., M.E. Hernandez, A. Kappler, R.E. Mielke, J.A. Gralnick, D.K. Newman. Shewanella oneidensis MR-1 uses overlapping pathways for iron reduction at a distance and by direct contact under conditions relevant for biofilms. Appl. Environ. Microbiol. Aug 1; 71:4414-4426.
Last updated: August 7, 2006
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